A review of sample handling considerations for reproductive and thyroid hormone measurement in serum or plasma

Rebecca L. Hegstad-Davies

doi:10.1016/j.theriogenology.2006.05.004

A review of sample handling considerations for reproductive and thyroid hormone measurement in serum or plasma

Rebecca L. Hegstad-Davies

Veterinary Population Medicine

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Inappropriate sample handling of blood, serum or plasma collected for the determination of hormone concentration may lead to inaccurate endocrine data and diagnoses. Many useful studies have been conducted to determine the potential effects of sample handling on measured hormone concentration. Unfortunately, because reported results frequently differ according to assay method, species studied and parameters measured, it is not always possible to predict the effect of specific sample handling scenarios as they are presented in practice. The objective of this review is to provide a summary of what has been reported in the literature regarding sample-handling procedures that may affect the measurement of hormone concentration in plasma or sera from animals being evaluated for reproductive function.

Original language	English (US)
Pages (from-to)	592-598
Number of pages	7
Journal	Theriogenology
Volume	66
Issue number	3 SPEC. ISS.
DOIs	https://doi.org/10.1016/j.theriogenology.2006.05.004
State	Published - Aug 2006

Keywords

Blood sample
Endocrinology
Hormone
Sample handling
Stability

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10.1016/j.theriogenology.2006.05.004

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abstract = "Inappropriate sample handling of blood, serum or plasma collected for the determination of hormone concentration may lead to inaccurate endocrine data and diagnoses. Many useful studies have been conducted to determine the potential effects of sample handling on measured hormone concentration. Unfortunately, because reported results frequently differ according to assay method, species studied and parameters measured, it is not always possible to predict the effect of specific sample handling scenarios as they are presented in practice. The objective of this review is to provide a summary of what has been reported in the literature regarding sample-handling procedures that may affect the measurement of hormone concentration in plasma or sera from animals being evaluated for reproductive function.",

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AB - Inappropriate sample handling of blood, serum or plasma collected for the determination of hormone concentration may lead to inaccurate endocrine data and diagnoses. Many useful studies have been conducted to determine the potential effects of sample handling on measured hormone concentration. Unfortunately, because reported results frequently differ according to assay method, species studied and parameters measured, it is not always possible to predict the effect of specific sample handling scenarios as they are presented in practice. The objective of this review is to provide a summary of what has been reported in the literature regarding sample-handling procedures that may affect the measurement of hormone concentration in plasma or sera from animals being evaluated for reproductive function.

KW - Blood sample

KW - Endocrinology

KW - Hormone

KW - Sample handling

KW - Stability

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JO - Theriogenology

JF - Theriogenology

IS - 3 SPEC. ISS.

ER -

A review of sample handling considerations for reproductive and thyroid hormone measurement in serum or plasma

Abstract

Keywords

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