A review of sample handling considerations for reproductive and thyroid hormone measurement in serum or plasma

Rebecca L. Hegstad-Davies

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Inappropriate sample handling of blood, serum or plasma collected for the determination of hormone concentration may lead to inaccurate endocrine data and diagnoses. Many useful studies have been conducted to determine the potential effects of sample handling on measured hormone concentration. Unfortunately, because reported results frequently differ according to assay method, species studied and parameters measured, it is not always possible to predict the effect of specific sample handling scenarios as they are presented in practice. The objective of this review is to provide a summary of what has been reported in the literature regarding sample-handling procedures that may affect the measurement of hormone concentration in plasma or sera from animals being evaluated for reproductive function.

Original languageEnglish (US)
Pages (from-to)592-598
Number of pages7
JournalTheriogenology
Volume66
Issue number3 SPEC. ISS.
DOIs
StatePublished - Aug 2006

Keywords

  • Blood sample
  • Endocrinology
  • Hormone
  • Sample handling
  • Stability

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