A rare case of pulmonary hyalinizing granuloma with calcification in a 5 year old boy

Vasu Gooty, Charles Harris, Andre Muelenaer, Brian Watson, Shawn D. Safford

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2 Scopus citations


Pulmonary hyalinizing granuloma (PHG) is a rare benign pulmonary nodular lesion of unknown etiology. We present a case of a 5-year-old boy who was found to have a chest mass while being evaluated for abdominal pain. He underwent a CXR and CT scan that showed popcorn calcifications in the right posterior mediastinum and within the hilum of right lung. These lesions were suspicious for benign calcified lymph nodes and follow-up chest CT after 3.5 months showed no interval changes in the calcified mediastinal masses. Extensive testing ruled out infectious diseases and malignancies. Given the unknown etiology of the lesions, he underwent VATS biopsy that demonstrated a nodular lesion characterized by a peripheral rim of fibrous tissue and central zone of necrosis and calcification, findings consistent with hyalinizing granuloma. PHG is extremely rare in pediatric age group. Although diagnosis of this condition is made by radiological and histopathological findings, it is important to rule out other causes of chest masses. Most of the patients usually have good prognosis with this rare disorder.

Original languageEnglish (US)
Pages (from-to)123-126
Number of pages4
JournalJournal of Pediatric Surgery Case Reports
Issue number3
StatePublished - Mar 2015

Bibliographical note

Publisher Copyright:
© 2015 The Authors.


  • Chest mass
  • Fungal hyphae
  • Histopathology
  • Histoplasmosis
  • Immunological disorder
  • Key words Hyalinizing granuloma
  • PPD
  • Popcorn calcification
  • Tuberculosis
  • VATS


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