A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression

Jennifer A. Linde; Gregory E. Simon; Evette J. Ludman; Laura E. Ichikawa; Belinda H. Operskalski; David Arterburn; Paul Rohde; Emily A. Finch; Robert W. Jeffery

doi:10.1007/s12160-010-9232-2

A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression

Jennifer A. Linde
, Gregory E. Simon
, Evette J. Ludman
, Laura E. Ichikawa
, Belinda H. Operskalski
, David Arterburn
, Paul Rohde
, Emily A. Finch
, Robert W. Jeffery

Research output: Contribution to journal › Article › peer-review

84 Scopus citations

Abstract

Background: Obesity is associated with clinical depression among women. However, depressed women are often excluded from weight loss trials. Purpose: This study examined treatment outcomes among women with comorbid obesity and depression. Methods: Two hundred three (203) women were randomized to behavioral weight loss (n∈=∈102) or behavioral weight loss combined with cognitive-behavioral depression management (n∈=∈101). Results: Average participant age was 52 years; mean baseline body mass index was 39 kg/m ². Mean Patient Health Questionnaire and Hopkins Symptom Checklist (SCL-20) scores indicated moderate to severe baseline depression. Weight loss and SCL-20 changes did not differ between groups at 6 or 12 months in intent-to-treat analyses (p∈=∈0.26 and 0.55 for weight, p∈=∈0.70 and 0.25 for depressive symptoms). Conclusions: Depressed obese women lost weight and demonstrated improved mood in both treatment programs. Future weight loss trials are encouraged to enroll depressed women.

Original language	English (US)
Pages (from-to)	119-130
Number of pages	12
Journal	Annals of Behavioral Medicine
Volume	41
Issue number	1
DOIs	https://doi.org/10.1007/s12160-010-9232-2
State	Published - Feb 2011

Bibliographical note

Funding Information:
Acknowledgments This study was funded by National Institutes of Health Grant R01MH068127 (G. E. Simon, PI); ClinicalTrials.gov identifier: NCT00169273, “Epidemiology and Care of Comorbid Obesity and Depression.” Conflict of Interest Statement The authors have no conflicts of interest to disclose.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Comorbidity
Depression
Intervention
Obesity
Women

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10.1007/s12160-010-9232-2

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Linde, J. A., Simon, G. E., Ludman, E. J., Ichikawa, L. E., Operskalski, B. H., Arterburn, D., Rohde, P., Finch, E. A., & Jeffery, R. W. (2011). A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression. Annals of Behavioral Medicine, 41(1), 119-130. https://doi.org/10.1007/s12160-010-9232-2

A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression. / Linde, Jennifer A.; Simon, Gregory E.; Ludman, Evette J. et al.
In: Annals of Behavioral Medicine, Vol. 41, No. 1, 02.2011, p. 119-130.

Research output: Contribution to journal › Article › peer-review

Linde, JA, Simon, GE, Ludman, EJ, Ichikawa, LE, Operskalski, BH, Arterburn, D, Rohde, P, Finch, EA & Jeffery, RW 2011, 'A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression', Annals of Behavioral Medicine, vol. 41, no. 1, pp. 119-130. https://doi.org/10.1007/s12160-010-9232-2

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abstract = "Background: Obesity is associated with clinical depression among women. However, depressed women are often excluded from weight loss trials. Purpose: This study examined treatment outcomes among women with comorbid obesity and depression. Methods: Two hundred three (203) women were randomized to behavioral weight loss (n∈=∈102) or behavioral weight loss combined with cognitive-behavioral depression management (n∈=∈101). Results: Average participant age was 52 years; mean baseline body mass index was 39 kg/m 2. Mean Patient Health Questionnaire and Hopkins Symptom Checklist (SCL-20) scores indicated moderate to severe baseline depression. Weight loss and SCL-20 changes did not differ between groups at 6 or 12 months in intent-to-treat analyses (p∈=∈0.26 and 0.55 for weight, p∈=∈0.70 and 0.25 for depressive symptoms). Conclusions: Depressed obese women lost weight and demonstrated improved mood in both treatment programs. Future weight loss trials are encouraged to enroll depressed women.",

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A randomized controlled trial of behavioral weight loss treatment versus combined weight loss/depression treatment among women with comorbid obesity and depression

Abstract

Bibliographical note

UN SDGs

Keywords

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