A randomized clinical trial on the efficacy of a new oxalate-containing sensitivity relief strip following professional vs self-application

M. A. Drake, P. A. Lenton, S. A. Lunos

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Objectives: The purpose of this study was to determine the efficacy of 3.14% dipotassium oxalate monohydrate-containing strip on the relief of dentinal hypersensitivity (DH). A second objective was to determine whether there was a difference in DH levels when the strip was self-applied vs applied by a dental professional. Methods: Sixty subjects were randomized into self-applied, professionally applied or placebo-strip groups. Dentinal hypersensitivity was evaluated by a blinded examiner, using the Schiff Air Scale (SAS). A verbal rating scale (VRS) was also used to measure the subjects’ perception of pain. Measures were taken at baseline, 30 minutes, 4 and 8 weeks post-treatment. Results: There was a significant reduction in DH in all three groups (P ≤.05) at 30 minutes and 8 weeks post-treatment. At the 4-week follow-up, only the self- and professionally applied (active ingredient) groups had a significant reduction in DH compared to baseline. When comparing the reduction in DH levels between groups, the only significant difference occurred between the professionally applied treatment group and the placebo group at the 4-week follow-up. There were no significant differences in DH reduction levels achieved between the self- and professionally applied groups (P >.05). Conclusions: This study confirmed the short-term (4 weeks) effectiveness of a single application of 3.14% dipotassium oxalate monohydrate-containing strip. Self- and professional application were not shown to be different.

Original languageEnglish (US)
Pages (from-to)e79-e87
JournalInternational journal of dental hygiene
Volume16
Issue number2
DOIs
StatePublished - May 2018

Bibliographical note

Funding Information:
Supported by scholarships from the University of Minnesota. The study protocol and informed consent form were approved by the University of Minnesota Human Research Protection Program (Institutional Review Board)

Keywords

  • dentinal hypersensitivity
  • oxalate
  • tooth sensitivity

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