A Randomized, Blinded, Controlled Clinical Study of Particulate Anorganic Bovine Bone Mineral and Calcium Phosphosilicate Putty Bone Substitutes for Socket Preservation

Georgios A. Kotsakis, Maurice Salama, Vanessa Chrepa, James E. Hinrichs, Philippe Gaillard

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82 Scopus citations

Abstract

Purpose: The purpose of this study was to compare the clinical efficacy of an anorganic bovine bone graft particulate to that of a calcium phosphosilicate putty alloplast for socket preservation. Materials and Methods: Thirty teeth were extracted from 24 patients. The sockets were debrided and received anorganic bovine bone mineral (BOV, n = 12), calcium phosphosilicate putty (PUT, n = 12), or no graft (CTRL, n = 6). The sockets were assessed clinically and radiographically 5 months later. Eight sockets in the BOV group and nine in the PUT group received implants 5 to 6 months postgrafting. The maximum implant insertion torque (MIT) was measured as an index of primary implant stability. The data were analyzed with the Mann-Whitney test. Results: Both test groups had statistically significantly less reduction in mean ridge width (BOV: 1.39 ± 0.57 mm; PUT: 1.26 ± 0.41 mm) in comparison to the control group (2.53 ± 0.59 mm). No statistically significant difference was identified between the test groups. MIT for PUT was ≤ 35 N/cm2 (MIT grade 4) for seven of the nine implants. MIT values in the BOV group ranged from grade 1 (10 to 19 N/cm2) to grade 4, which was statistically significantly lower than for the PUT group. The overall implant success rate was 94.1% (16 of 17 implants were successful). No implants were lost in the PUT group; one implant failed in the BOV group. Conclusion: Both tested bone substitutes can be recommended for preservation of alveolar ridge width following extraction. PUT might be more suitable for achieving primary stability for implants placed at 5 to 6 months postextraction. Int J Oral Maxillofac Implants 2014;29:141–151. doi: 10.11607/jomi.3230

Original languageEnglish (US)
Pages (from-to)141-151
Number of pages11
JournalInternational Journal of Oral and Maxillofacial Implants
Volume29
Issue number1
DOIs
StatePublished - Feb 14 2014

Bibliographical note

Funding Information:
This project was supported by grant number 1UL1RR033183 from the National Center for Research Resources and grant number 8UL1TR000114-02 from the National Center for Advancing Translational Sciences of the National Institutes of Health to the University of Minnesota Clinical and Translational Science Institute. The authors wish to thank Novabone Products LLC, Alachua, Florida, for providing partial support for the test materials that were used in this study. The authors declare that they have no conflicts of interest.

Funding Information:
This project was supported by grant number 1UL1RR033183 from the National Center for Research Resources and grant number 8UL1TR000114-02 from the National Center for Advancing Translational Sciences of the National Institutes of Health to the University of Minnesota Clinical and Translational Science Institute. The authors wish to thank Novabone Products LLC, Alachua, Florida, for providing partial support for the test materials that were used in this study.

Publisher Copyright:
© 2014. by Quintessence Publishing Co Inc.

Keywords

  • bone graft
  • dental putty
  • insertion torque
  • primary implant stability
  • socket preservation
  • tooth extraction

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