This study reports the first comprehensive data on the effects of glycerol, a widely used cryoprotective agent (CPA), on the thermal properties of Phosphate Buffered Saline at subzero and cryogenic (≤-40 °C) temperatures. A Differential Scanning Calorimeter was used to measure specific and latent heats. Thermal conductivity was determined using a thermistor probe technique. Results differed significantly from known water (ice) or glycerol values, and a simple weight averaging method between water and glycerol was found to over-predict thermal conductivity below -100 °C due to glass formation. This indicates the need for these newly measured thermal properties of CPA solutions particularly below -100 °C.
|Original language||English (US)|
|Number of pages||10|
|Journal||International Journal of Heat and Mass Transfer|
|State||Published - Feb 2008|
Bibliographical noteFunding Information:
This work was supported by the United States National Science Foundation (NSF) under Grant No. CTS 0313934. The authors thank Dr. Willem F. Wolkers for a careful read of the manuscript.
Copyright 2008 Elsevier B.V., All rights reserved.
- Phosphate buffered saline
- Thermal property