A proposed mechanism of ALS fails the test in vivo

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations

Abstract

In contrast to prevailing hypotheses, a genetic study shows that the toxic gain of function associated with mutant superoxide dismutase in familial amyotropic lateral sclerosis is unlikely to be due to changes in its oxidative activity causing an increase in free radicals.

Original languageEnglish (US)
Pages (from-to)287-288
Number of pages2
JournalNature neuroscience
Volume5
Issue number4
DOIs
StatePublished - Apr 16 2002

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