A progressive-ILP-based routing algorithm for the synthesis of cross-referencing biochips

Ping Hung Yuh; Sachin S. Sapatnekar; Chia Lin Yang; Yao Wen Chang

doi:10.1109/TCAD.2009.2023196

A progressive-ILP-based routing algorithm for the synthesis of cross-referencing biochips

Ping Hung Yuh, Sachin S. Sapatnekar, Chia Lin Yang, Yao Wen Chang

Electrical and Computer Engineering

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Due to recent advances in microfluidics technology, digital microfluidic biochips and their associated computer-aided-design problems have gained much attention, most of which has been devoted to direct-addressing biochips. In this paper, we solve the droplet routing problem under the more scalable cross-referencing biochip paradigm. We propose the first droplet routing algorithm that directly solves the problem of routing. We first present an optimal basic integer-linear-programming (ILP) formulation. Due to its complexity, we also propose a progressive-ILP scheme to determine the locations of droplets at each time step. Simulation results demonstrate the efficiency and effectiveness of our algorithm.

Original language	English (US)
Article number	5208480
Pages (from-to)	1295-1306
Number of pages	12
Journal	IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
Volume	28
Issue number	9
DOIs	https://doi.org/10.1109/TCAD.2009.2023196
State	Published - Sep 2009

Keywords

Cross-referencing biochips
Integer linear programming (ILP)
Progressive
Routing

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10.1109/TCAD.2009.2023196

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title = "A progressive-ILP-based routing algorithm for the synthesis of cross-referencing biochips",

abstract = "Due to recent advances in microfluidics technology, digital microfluidic biochips and their associated computer-aided-design problems have gained much attention, most of which has been devoted to direct-addressing biochips. In this paper, we solve the droplet routing problem under the more scalable cross-referencing biochip paradigm. We propose the first droplet routing algorithm that directly solves the problem of routing. We first present an optimal basic integer-linear-programming (ILP) formulation. Due to its complexity, we also propose a progressive-ILP scheme to determine the locations of droplets at each time step. Simulation results demonstrate the efficiency and effectiveness of our algorithm.",

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AU - Yuh, Ping Hung

AU - Sapatnekar, Sachin S.

AU - Yang, Chia Lin

AU - Chang, Yao Wen

PY - 2009/9

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N2 - Due to recent advances in microfluidics technology, digital microfluidic biochips and their associated computer-aided-design problems have gained much attention, most of which has been devoted to direct-addressing biochips. In this paper, we solve the droplet routing problem under the more scalable cross-referencing biochip paradigm. We propose the first droplet routing algorithm that directly solves the problem of routing. We first present an optimal basic integer-linear-programming (ILP) formulation. Due to its complexity, we also propose a progressive-ILP scheme to determine the locations of droplets at each time step. Simulation results demonstrate the efficiency and effectiveness of our algorithm.

AB - Due to recent advances in microfluidics technology, digital microfluidic biochips and their associated computer-aided-design problems have gained much attention, most of which has been devoted to direct-addressing biochips. In this paper, we solve the droplet routing problem under the more scalable cross-referencing biochip paradigm. We propose the first droplet routing algorithm that directly solves the problem of routing. We first present an optimal basic integer-linear-programming (ILP) formulation. Due to its complexity, we also propose a progressive-ILP scheme to determine the locations of droplets at each time step. Simulation results demonstrate the efficiency and effectiveness of our algorithm.

KW - Cross-referencing biochips

KW - Integer linear programming (ILP)

KW - Progressive

KW - Routing

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A progressive-ILP-based routing algorithm for the synthesis of cross-referencing biochips

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