This paper presents a fully-integrated stimulator chip for electrical microstimulation. The device is designed in a high-voltage process that allows up to 20V power supply and 19V output voltage compliance. A broad range of current-mode stimulation waveforms and patterns can be generated, including symmetrical/asymmetrical, biphasic/monophasic, and pulse train stimuli. The current amplitude, pulse width, and stimulation rate are adjustable from 0.5μA to 2mA, 100μs to 4ms, and 0.1Hz to 200Hz, respectively. Two complementary charge-balancing techniques are integrated to reduce residual voltage and stimulation artifacts. In in vitro experiments, the stimulator is demonstrated to trigger neural spikes, modulate neuronal firing rate, and alter mesoscopic neuronal activity. The results suggest the proposed microstimulator can support a wide variety of neuroscience experiments that require electrical microstimulation.
|Original language||English (US)|
|Title of host publication||Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016|
|Publisher||Institute of Electrical and Electronics Engineers Inc.|
|Number of pages||4|
|State||Published - 2016|
|Event||12th IEEE Biomedical Circuits and Systems Conference, BioCAS 2016 - Shanghai, China|
Duration: Oct 17 2016 → Oct 19 2016
|Name||Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016|
|Other||12th IEEE Biomedical Circuits and Systems Conference, BioCAS 2016|
|Period||10/17/16 → 10/19/16|
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© 2016 IEEE.