TY - JOUR
T1 - A Predator Unmasked
T2 - Life Cycle of Bdellovibrio bacteriovorus from a Genomic Perspective
AU - Rendulic, Snjezana
AU - Jagtap, Pratik
AU - Rosinus, Andrea
AU - Eppinger, Mark
AU - Baar, Claudia
AU - Lanz, Christa
AU - Keller, Heike
AU - Lambert, Carey
AU - Evans, Katy J.
AU - Goesmann, Alexander
AU - Meyer, Folker
AU - Sockett, R. Elizabeth
AU - Schuster, Stephan C.
PY - 2004/1/30
Y1 - 2004/1/30
N2 - Predatory bacteria remain molecularly enigmatic, despite their presence in many microbial communities. Here we report the complete genome of Bdellovibrio bacteriovorus HD100, a predatory Gram-negative bacterium that invades and consumes other Gram-negative bacteria. Its surprisingly large genome shows no evidence of recent gene transfer from its prey. A plethora of paralogous gene families coding for enzymes, such as hydrolases and transporters, are used throughout the life cycle of B. bacteriovorus for prey entry, prey killing, and the uptake of complex molecules.
AB - Predatory bacteria remain molecularly enigmatic, despite their presence in many microbial communities. Here we report the complete genome of Bdellovibrio bacteriovorus HD100, a predatory Gram-negative bacterium that invades and consumes other Gram-negative bacteria. Its surprisingly large genome shows no evidence of recent gene transfer from its prey. A plethora of paralogous gene families coding for enzymes, such as hydrolases and transporters, are used throughout the life cycle of B. bacteriovorus for prey entry, prey killing, and the uptake of complex molecules.
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U2 - 10.1126/science.1093027
DO - 10.1126/science.1093027
M3 - Article
C2 - 14752164
AN - SCOPUS:9144236808
SN - 0036-8075
VL - 303
SP - 689
EP - 692
JO - Science
JF - Science
IS - 5658
ER -