A precise, continuous recording clot timer based on a thermometric detection system

W. D. Bostick, P. W. Carr

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A plasma and blood coagulation time detector is described. The instrument utilizes a conventional glass probe thermistor mounted in a vibratory mixer as the detection element. Both the initiation and the end point of the coagulation process are registered on a strip chart recorder. A precision of 2 to 4% in end point time has been obtained in both the normal and therapeutic prothrombin time ranges. The end point as determined by this method has a correlation coefficient of 0.98 at the 99.5% confidence interval with the Fibrometer method.

Original languageEnglish (US)
Pages (from-to)330-336
Number of pages7
JournalAmerican journal of clinical pathology
Volume60
Issue number3
DOIs
StatePublished - 1973

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