TY - JOUR
T1 - A pilot study of functional magnetic resonance imaging brain correlates of deception in healthy young men
AU - Kozel, F. Andrew
AU - Revell, Letty J.
AU - Lorberbaum, Jeffrey P.
AU - Shastri, Ananda
AU - Elhai, Jon D.
AU - Horner, Michael David
AU - Smith, Adam
AU - Nahas, Ziad
AU - Bohning, Daryl E.
AU - George, Mark S.
PY - 2004/1/1
Y1 - 2004/1/1
N2 - We hypothesized that specific brain regions would activate during deception, and these areas would correlate with changes in electrodermal activity (EDA). Eight men were asked to find money hidden under various objects. While functional MRI images were acquired and EDA was recorded, the subjects gave both truthful and deceptive answers regarding the money's location. The group analysis revealed significant activation during deception in the orbitofrontal cortex (OFCx) and anterior cingulate (AC), but individual results were not consistent. Individually and as a group, EDA correlated with blood flow changes in the OFCx and AC. Specific brain regions were activated during deception, but the present technique lacks good predictive power for individuals.
AB - We hypothesized that specific brain regions would activate during deception, and these areas would correlate with changes in electrodermal activity (EDA). Eight men were asked to find money hidden under various objects. While functional MRI images were acquired and EDA was recorded, the subjects gave both truthful and deceptive answers regarding the money's location. The group analysis revealed significant activation during deception in the orbitofrontal cortex (OFCx) and anterior cingulate (AC), but individual results were not consistent. Individually and as a group, EDA correlated with blood flow changes in the OFCx and AC. Specific brain regions were activated during deception, but the present technique lacks good predictive power for individuals.
UR - http://www.scopus.com/inward/record.url?scp=4544294534&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4544294534&partnerID=8YFLogxK
U2 - 10.1176/jnp.16.3.295
DO - 10.1176/jnp.16.3.295
M3 - Article
C2 - 15377736
AN - SCOPUS:4544294534
VL - 16
SP - 295
EP - 305
JO - Journal of Neuropsychiatry and Clinical Neurosciences
JF - Journal of Neuropsychiatry and Clinical Neurosciences
SN - 0895-0172
IS - 3
ER -