A phytotoxin solanapyrone-a downregulates calcium-dependent protein kinase activity in potato

A. Hassan, N. Hatsugai, M. M. Shah

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

We previously demonstrated that alternaric acid, a host-specific toxin produced by the plant pathogenic fungus Alternaria solani, in the presence of Ca2+ and Mg2+, stimulated in vitro phosphorylation of His-tagged calcium-dependent protein kinase 2 from potato cultivar Rishiri (RiCDPK2). Herein, we report that Solanapyrone-A (SpA), a non-host-specific toxin produced by A. solani, inhibited the phosphorylation of RiCDPK2 in the presence of Ca2+ and Mg2+. However, SpA stimulated RiCDPK2 phosphorylation in the absence of these cations. Based on the current findings, we suggest that RiCDPK2 may mediate SpA-induced signaling independent of Ca2+ and Mg2+, leading to a compatible interaction between potato and A. solani.

Original languageEnglish (US)
Pages (from-to)1540-1545
Number of pages6
JournalGenetics and Molecular Research
Volume12
Issue number2
DOIs
StatePublished - May 13 2013

Keywords

  • Alternaria solani
  • CDPK
  • Potato
  • Solanapyrone-a
  • Solanum tuberosum x s. demissum
  • Suppressor

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