A one-step synthesis of a deuterated paclitaxel analogue: 10-deacetoxy- (10α-2H)paclitaxel

Dinah Dutta, Harry Hadd, David G. Vander Velde, Gunda I. Georg

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

10-Deacetoxy-(10α-2H)paclitaxel was prepared in one step via the samarium diiodide mediated deoxygenation of paclitaxel in the presence of D2O.

Original languageEnglish (US)
Pages (from-to)3277-3278
Number of pages2
JournalBioorganic and Medicinal Chemistry Letters
Volume9
Issue number23
DOIs
StatePublished - Dec 6 1999

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