A new UCP1-independent thermogenic mechanism in peroxisomes

Anthony R.P. Verkerke; Shingo Kajimura

doi:10.1016/j.molcel.2025.10.016

A new UCP1-independent thermogenic mechanism in peroxisomes

Anthony R.P. Verkerke
, Shingo Kajimura

Physiology

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

In a recent publication in Nature , Liu et al. report a UCP1-independent thermogenic mechanism in which peroxisomes generate heat in brown adipose tissue through active synthesis and oxidation of monomethyl branched-chain fatty acids (mmBCFAs) derived from branched-chain amino acids.

Original language	English (US)
Pages (from-to)	3895-3897
Number of pages	3
Journal	Molecular Cell
Volume	85
Issue number	21
DOIs	https://doi.org/10.1016/j.molcel.2025.10.016
State	Published - Nov 6 2025

Bibliographical note

Publisher Copyright:
© 2025 Elsevier Inc.

PubMed: MeSH publication types

Journal Article

Publisher link

10.1016/j.molcel.2025.10.016

Find It

Find It at U of M Libraries

Cite this

@article{fcefa89d2dd64838921bcf9536325b2d,

title = "A new UCP1-independent thermogenic mechanism in peroxisomes",

abstract = "In a recent publication in Nature , Liu et al. report a UCP1-independent thermogenic mechanism in which peroxisomes generate heat in brown adipose tissue through active synthesis and oxidation of monomethyl branched-chain fatty acids (mmBCFAs) derived from branched-chain amino acids.",

author = "Verkerke, \{Anthony R.P.\} and Shingo Kajimura",

note = "Publisher Copyright: {\textcopyright} 2025 Elsevier Inc.",

year = "2025",

month = nov,

day = "6",

doi = "10.1016/j.molcel.2025.10.016",

language = "English (US)",

volume = "85",

pages = "3895--3897",

journal = "Molecular Cell",

issn = "1097-2765",

publisher = "Cell Press",

number = "21",

}

TY - JOUR

T1 - A new UCP1-independent thermogenic mechanism in peroxisomes

AU - Verkerke, Anthony R.P.

AU - Kajimura, Shingo

PY - 2025/11/6

Y1 - 2025/11/6

N2 - In a recent publication in Nature , Liu et al. report a UCP1-independent thermogenic mechanism in which peroxisomes generate heat in brown adipose tissue through active synthesis and oxidation of monomethyl branched-chain fatty acids (mmBCFAs) derived from branched-chain amino acids.

AB - In a recent publication in Nature , Liu et al. report a UCP1-independent thermogenic mechanism in which peroxisomes generate heat in brown adipose tissue through active synthesis and oxidation of monomethyl branched-chain fatty acids (mmBCFAs) derived from branched-chain amino acids.

UR - https://www.scopus.com/pages/publications/105021068849

UR - https://www.scopus.com/pages/publications/105021068849#tab=citedBy

U2 - 10.1016/j.molcel.2025.10.016

DO - 10.1016/j.molcel.2025.10.016

M3 - Comment/debate

C2 - 41202803

AN - SCOPUS:105021068849

SN - 1097-2765

VL - 85

SP - 3895

EP - 3897

JO - Molecular Cell

JF - Molecular Cell

IS - 21

ER -

A new UCP1-independent thermogenic mechanism in peroxisomes

Abstract

Bibliographical note

PubMed: MeSH publication types

Publisher link

Find It

Other files and links

Fingerprint

Cite this