Abstract
A one‐pot preparation of carboximidamides (amidines) 11–14 involves treatment of amides 2–5 with phosphorus pentachloride followed by the treatment of the resultant crude imidoyl chlorides 7–10 with ammonia. Amidines 11–14 are cyclized to quinazolines 20–26 in lithium alkylamide‐or dialkylamide‐mediated reactions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 703-706 |
| Number of pages | 4 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 29 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jul 1992 |
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Dive into the research topics of 'A new synthesis of N‐substituted‐2‐alkyl(or aryl)quinazolin‐4‐amines by amide base‐mediated cyclization of carbox‐imidamides derived from 2‐(trifluoromethyl)benzenamine'. Together they form a unique fingerprint.Cite this
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