Abstract
Accurate mass measurements of 20 drugs were conducted using MassWorks software on a TSQ Quantum Ultra mass spectrometer. All Q1 scan mass spectral data were collected in profile mode with full width at half-maximum (FWHM) set at 0. 7 Da. The mass errors of all 20 drugs (molecular weight between 135 and 810) were within the range from - 22. 4 × 10-6 to 36. 1 × 10-6, among them 90% of the drugs achieved a mass accuracy better than 10 × 10-6. The new method can provide accurate mass measurements on unit mass resolution mass spectrometers.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1112-1114 |
| Number of pages | 3 |
| Journal | Yaoxue Xuebao |
| Volume | 42 |
| Issue number | 10 |
| State | Published - Oct 1 2007 |
Keywords
- Accurate relative molecular mass
- Isotope
- Unit mass resolution mass spectrometer