A new look at dry eye disease and its treatment

J. Daniel Nelson; Harold Helms; Richard Fiscella; Yvonne Southwell; Jan D. Hirsch

doi:10.1007/BF02854841

A new look at dry eye disease and its treatment

J. Daniel Nelson
, Harold Helms
, Richard Fiscella
, Yvonne Southwell
, Jan D. Hirsch

Research output: Contribution to journal › Review article › peer-review

87 Scopus citations

Abstract

This review examines the impact of moderate to severe dry eye disease on daily life and medical-resource utilization. The results suggest that current treatment paradigms can lead to unacceptable costs in both quality of life and progressive use of healthcare resources. Evidence linking this disease to T-cell-mediated inflammatory processes lays the foundation for understanding the clinical benefits of topical cyclosporine, an immunomodulatory and anti- inflammatory agent.

Original language	English (US)
Pages (from-to)	84-93
Number of pages	10
Journal	Advances in Therapy
Volume	17
Issue number	2
DOIs	https://doi.org/10.1007/BF02854841
State	Published - 2000
Externally published	Yes

Keywords

Cyclosporine
Dry eye
Inflammatory response

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10.1007/BF02854841

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abstract = "This review examines the impact of moderate to severe dry eye disease on daily life and medical-resource utilization. The results suggest that current treatment paradigms can lead to unacceptable costs in both quality of life and progressive use of healthcare resources. Evidence linking this disease to T-cell-mediated inflammatory processes lays the foundation for understanding the clinical benefits of topical cyclosporine, an immunomodulatory and anti- inflammatory agent.",

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AU - Fiscella, Richard

AU - Southwell, Yvonne

AU - Hirsch, Jan D.

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Y1 - 2000

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AB - This review examines the impact of moderate to severe dry eye disease on daily life and medical-resource utilization. The results suggest that current treatment paradigms can lead to unacceptable costs in both quality of life and progressive use of healthcare resources. Evidence linking this disease to T-cell-mediated inflammatory processes lays the foundation for understanding the clinical benefits of topical cyclosporine, an immunomodulatory and anti- inflammatory agent.

KW - Cyclosporine

KW - Dry eye

KW - Inflammatory response

UR - https://www.scopus.com/pages/publications/0033916501

UR - https://www.scopus.com/pages/publications/0033916501#tab=citedBy

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JO - Advances in Therapy

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ER -

A new look at dry eye disease and its treatment

Abstract

Keywords

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