A new flavor of entry exclusion in ICE elements provides a selective advantage for the element and its host

Gary M. Dunny; Helmut Hirt

doi:10.1111/mmi.14342

A new flavor of entry exclusion in ICE elements provides a selective advantage for the element and its host

Gary M. Dunny, Helmut Hirt

Microbiology

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

Entry exclusion has been described in many bacterial conjugation systems, but their molecular mechanisms are not well understood. In the current issue, Avello et al. describe a new exclusion system in the conjugative element ICEBs1. They identify the yddJ gene as the functional exclusion gene and its target as the protein product of the conG gene. They provide evidence for a possible mechanism and for the contribution of the system to reduce fitness costs of ICE expression.

Original language	English (US)
Pages (from-to)	1061-1065
Number of pages	5
Journal	Molecular Microbiology
Volume	112
Issue number	4
DOIs	https://doi.org/10.1111/mmi.14342
State	Published - Oct 1 2019

Bibliographical note

Funding Information:
Our conjugation research is supported by PHS Grant R35GM118079 from the NIH.

Publisher Copyright:
© 2019 John Wiley & Sons Ltd

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10.1111/mmi.14342

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abstract = "Entry exclusion has been described in many bacterial conjugation systems, but their molecular mechanisms are not well understood. In the current issue, Avello et al. describe a new exclusion system in the conjugative element ICEBs1. They identify the yddJ gene as the functional exclusion gene and its target as the protein product of the conG gene. They provide evidence for a possible mechanism and for the contribution of the system to reduce fitness costs of ICE expression.",

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A new flavor of entry exclusion in ICE elements provides a selective advantage for the element and its host

Abstract

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