TY - JOUR
T1 - A network of rice genes associated with stress response and seed development
AU - Cooper, Bret
AU - Clarke, Joseph D.
AU - Budworth, Paul
AU - Kreps, Joel
AU - Hutchison, Don
AU - Park, Sylvia
AU - Guimil, Sonia
AU - Dunn, Molly
AU - Luginbühl, Peter
AU - Ellero, Cinzia
AU - Goff, Stephen A.
AU - Glazebrook, Jane
PY - 2003/4/15
Y1 - 2003/4/15
N2 - We used a systematic approach to build a network of genes associated with developmental and stress responses in rice by identifying interaction domains for 200 proteins from stressed and developing tissues, by measuring the associated gene expression changes in different tissues exposed to a variety of environmental, biological, and chemical stress treatments, and by localizing the cognate genes to regions of stress-tolerance trait genetic loci. The integrated data set suggests that similar genes respond to environmental cues and stresses, and some may also regulate development. We demonstrate that the data can be used to correctly predict gene function in monocots and dicots. As a result, we have identified five genes that contribute to disease resistance in Arabidopsis.
AB - We used a systematic approach to build a network of genes associated with developmental and stress responses in rice by identifying interaction domains for 200 proteins from stressed and developing tissues, by measuring the associated gene expression changes in different tissues exposed to a variety of environmental, biological, and chemical stress treatments, and by localizing the cognate genes to regions of stress-tolerance trait genetic loci. The integrated data set suggests that similar genes respond to environmental cues and stresses, and some may also regulate development. We demonstrate that the data can be used to correctly predict gene function in monocots and dicots. As a result, we have identified five genes that contribute to disease resistance in Arabidopsis.
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U2 - 10.1073/pnas.0737574100
DO - 10.1073/pnas.0737574100
M3 - Article
C2 - 12684538
AN - SCOPUS:0037447263
SN - 0027-8424
VL - 100
SP - 4945
EP - 4950
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 8
ER -