A multiscale model of cardiac concentric hypertrophy incorporating both mechanical and hormonal drivers of growth

Keyphrases

• Transverse Aortic Constriction 100%
• Concentric Hypertrophy 100%
• Growth Drivers 100%
• Transgenic 25%
• Signaling Pathway 25%
• Overexpression 25%
• Response Exercise 25%
• Beta-blockers 25%
• Attenuation 25%
• Hypertrophy 25%
• Left Ventricle 25%
• Network Model 25%
• Angiotensin Receptor Blockers 25%
• Cardiac Hypertrophy 25%
• Knock 25%
• Propranolol 25%
• Cellular Level 25%
• Finite Element Model 25%
• Growth Pattern 25%
• Afterload 25%
• Wall Stress 25%
• Losartan 25%
• Isoproterenol 25%
• Hormone Levels 25%
• Pharmacologic Interventions 25%
• Hormonal Signaling 25%
• In Vitro Growth 25%
• Genetic Interventions 25%
• Mechanical Signals 25%
• Hypertrophy Signaling 25%
• Data Trends 25%
• In Vivo Data 25%
• Adrenergic Signaling Pathway 25%
• Receptor Inhibitors 25%
• Growth Trend 25%
• Gq-coupled Receptor 25%

Medicine and Dentistry

• Aortic Constriction 100%
• Signal Transduction 50%
• Ventricular Hypertrophy 25%
• Receptor 25%
• Noradrenalin 25%
• Infusion 25%
• Angiotensin Receptor Antagonist 25%
• Left Ventricle 25%
• Afterload 25%
• Losartan 25%
• Knock Out 25%
• Hormone Determination 25%
• Finite Element Analysis 25%
• Propranolol 25%
• Isoprenaline 25%
• Genetics 25%

Biochemistry, Genetics and Molecular Biology

• Mechanics 100%
• Signal Transduction 40%
• Genetics 20%
• Wall Stress 20%
• Transgenics 20%
• Cell Level 20%
• Heart Afterload 20%
• Angiotensin Receptor 20%
• Norepinephrine 20%
• Isoprenaline 20%
• Propranolol 20%