Although a single-stage off-line LED driver can achieve low cost and high efficiency, the notorious double-line-frequency flicker issue with a single-stage LED driver limits its usage in high-quality lighting applications. To solve lighting flicker, multiplexing operation is proposed in this paper. One switching cycle is further divided into two portions, namely phase one and phase two, which produces a main output voltage and an opposite ripple voltage. The main and the opposite ripple voltage are connected in series to form the LED voltage, which is a DC because of ripple cancellation. Therefore, a DC LED current can be produced and achieves flicker-free LED driving performance. A 7.5W experimental prototype had been built and tested to verify the design concept.