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A mouse model of accelerated liver aging caused by a defect in DNA repair
Siobhán Q. Gregg
, Verónica Gutiérrez
, Andria Rasile Robinson
, Tyler Woodell
, Atsunori Nakao
, Mark A. Ross
, George K. Michalopoulos
, Lora Rigatti
, Carrie E. Rothermel
, Irene Kamileri
, George Garinis
, Donna Beer Stolz
,
Laura J. Niedernhofer
Research output
:
Contribution to journal
›
Article
›
peer-review
110
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Scopus citations
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Keyphrases
Mouse Model
100%
DNA Repair
100%
ERCC1
100%
Liver Aging
100%
Liver
33%
Wild Mice
33%
Age-related
22%
Murine Model
22%
Normal Aging
22%
Liver Changes
22%
Accelerated Aging
22%
Aging
11%
Fibrosis
11%
Regenerability
11%
Liver Dysfunction
11%
DNA Damage
11%
Hypothesis Testing
11%
Oxidative Damage
11%
Senescence
11%
Albumin
11%
Liver Disease
11%
Lipid Hydroperoxides
11%
Partial Hepatectomy
11%
Increased Incidence
11%
Liver Enzymes
11%
Acute Inflammation
11%
Insults
11%
Acrolein
11%
Transcriptional Changes
11%
Changes with Age
11%
Emerging Adulthood
11%
Area of Necrosis
11%
Liver Damage
11%
Lipofuscin
11%
Inherited Defect
11%
Steatosis
11%
Hepatocellular Degeneration
11%
Progeroid Syndrome
11%
Progeroid
11%
Pseudocapillarization
11%
Progerias
11%
DNA Repair Defects
11%
Anisokaryosis
11%
Hepatic Architecture
11%
Age Profile
11%
Medicine and Dentistry
DNA Repair
100%
Accelerated Aging
66%
Serositis
33%
Liver Injury
33%
Necrosis
33%
Fibrosis
33%
DNA Damage
33%
Liver Disease
33%
Partial Hepatectomy
33%
Albumin
33%
Liver Enzyme
33%
Liver Dysfunction
33%
Lipofuscin
33%
Lipid Hydroperoxide
33%
Progeroid Syndromes
33%
Steatosis
33%
Acrolein
33%
Diseases
33%
Pharmacology, Toxicology and Pharmaceutical Science
Mouse Model
100%
Wild Type Mouse
100%
Acrolein
33%
Syndrome
33%
Liver Dysfunction
33%
Liver Disease
33%
Liver Injury
33%
Necrosis
33%
Lipid Hydroperoxide
33%
Liver Enzyme
33%
Steatosis
33%
Inflammation
33%
Fibrosis
33%
Lipofuscin
33%
Albumin
33%
Diseases
33%
Biochemistry, Genetics and Molecular Biology
Mouse Model
100%
DNA Repair
100%
Wild Type Mouse
100%
Wild Type
66%
Acrolein
33%
Enzyme
33%
DNA Damage
33%
Albumin
33%
Lipid
33%