A microculture syncytia assay for the detection of bovine leukemia virus (BLV) has been described and compared with the conventional macroculture assay. The microculture assay required fewer indicator cells, was as sensitive as the macroculture assay and provided a reproducible test for the detection and titration of BLV.
Bibliographical noteFunding Information:
We wish to thank Mr. David A. Warner for his excellentt echnicala ssistance. This i n v e s t i g a t i o nw a s s u p p o r t e db y Grant Number 17232 a w a r d e db y the National Cancer I n s t i t u t e ,D H E W and Contract Number EY-76-S-02-0910.* 000 from the U.S. Energy Researcha nd DevelopmenAt dministration.