A longitudinal study of parent-reported sensory responsiveness in toddlers at-risk for autism

The Ibis Network

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11 Scopus citations

Abstract

Background: Atypical sensory responsivity and sensory interests are now included in the DSM 5 diagnostic criteria for autism spectrum disorder (ASD) under the broad domain of restricted and repetitive behavior (RRB). However, relatively little is known about the emergence of sensory-related features and their relation to conventionally defined RRB in the first years of life. Methods: Prospective, longitudinal parent-report data using the Sensory Experiences Questionnaire (SEQ) were collected for 331 high-risk toddlers (74 of whom met diagnostic criteria for ASD at age 2) and 135 low-risk controls. Longitudinal profiles for SEQ scores were compared between groups across ages 12–24 months. Associations between SEQ measures and measures of RRB subtypes (based on the Repetitive Behavior Scale, Revised) were also examined. Results: Longitudinal profiles for all SEQ scores significantly differed between groups. SEQ scores were elevated for the ASD group from age 12 months, with differences becoming more pronounced across the 12–24 month interval. At both 12 and 24 months, most measures derived from the SEQ were significantly associated with all subtypes of RRB. Conclusions: These findings suggest that differences in sensory responsivity may be evident in high-risk infants later diagnosed with ASD in early toddlerhood, and that the magnitude of these differences increases over the second year of life. The high degree of association between SEQ scores and RRB supports the conceptual alignment of these features but also raises questions as to explanatory mechanisms.

Original languageEnglish (US)
Pages (from-to)314-324
Number of pages11
JournalJournal of Child Psychology and Psychiatry and Allied Disciplines
Volume60
Issue number3
DOIs
StatePublished - Mar 2019

Bibliographical note

Funding Information:
This study was supported by funds from the National Institutes of Health under awards R01-HD055741 and P30-HD003110 to JP and K01-MH101653 to JW. Additional funding support has been provided from Autism Speaks and the Simons Foundation (SFARI Grant 140209). The funders had no role in study design, data collection, analysis, data interpretation, or the writing of the report. The authors would like to thank the IBIS families for their continued participation in this research. The authors have declared that they have no competing or potential conflicts of interest.

Funding Information:
The Infant Brain Imaging Study (IBIS) Network is an NIH funded Autism Center of Excellence project and consists of a consortium of 8 universities in the US and Canada. Clinical Sites: University of North Carolina: J. Piven (IBIS Network PI), H.C. Hazlett, C. Chappell; University of Washington: S. Dager, A. Estes, D. Shaw; Washington University: K. Botteron, R. McKinstry, J. Constantino, J. Pruett; Children’s Hospital of Philadelphia: R. Schultz, J. Pandey, S. Paterson; University of Alberta: L. Zwaigenbaum; University of Minnesota: J. Elison, J. Wolff; Data Coordinating Center: Montreal Neurological Institute: A.C. Evans, D.L. Collins, G.B. Pike, V. Fonov, P. Kostopoulos, S. Das, L. MacIntyre; Image Processing Core: University of Utah: G. Gerig; University of North Carolina: M. Styner; Statistical Analysis Core: University of North Carolina: H. Gu.

Publisher Copyright:
© 2018 Association for Child and Adolescent Mental Health.

Keywords

  • Sensory
  • development
  • longitudinal
  • repetitive behavior

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