TY - JOUR
T1 - A longitudinal molecular surveillance study of human polyomavirus viremia in heart, kidney, liver, and pancreas transplant patients
AU - PV16000 Study Group
AU - Razonable, Raymund R.
AU - Brown, Robert A.
AU - Humar, Atul
AU - Covington, Emma
AU - Alecock, Emma
AU - Paya, Carlos V.
AU - Eris, Josie
AU - Keogh, Anne
AU - Mathew, Tim
AU - McCaughan, Geoff
AU - Nicholls, Kathy
AU - Strasser, Simone
AU - Lalonde, Richard
AU - Marotta, Paul
AU - Preiksaitis, Jutta
AU - Yoshida, Eric
AU - Gandjbakch, Iradj
AU - Lebranchu, Yvon
AU - Legendre, Christophe
AU - Saliba, Faouzi
AU - Traynor, Oscar
AU - Angeli, Paolo
AU - Menichetti, Francesco
AU - Gane, R.
AU - Bakran, Ali
AU - Forsythe, John
AU - Heaton, Nigel
AU - Lodge, Peter
AU - Manas, Derek
AU - Morris, Peter
AU - Parameshwar, Jayan
AU - Yonan, Nizar
AU - Alexander, Barbara
AU - Blumberg, Emily
AU - Brennan, Daniel C.
AU - Brown, Robert
AU - Busuttil, Ronald W.
AU - Chavin, Ken
AU - Conti, David
AU - DeMattos, Angelo
AU - Dominguez, Ed
AU - Eisen, Howard J.
AU - Fishbein, Dan
AU - Fishbein, Thomas
AU - Fisher, Robert
AU - Freeman, Richard
AU - Freise, Chris
AU - Hart, Marquis
AU - Heffron, Thomas
AU - Howard, Richard J.
PY - 2005/10/15
Y1 - 2005/10/15
N2 - In this study of 263 heart, kidney, liver, and pancreas transplant patients, BK virus (BKV) and JC virus (JCV) DNAemia were observed most commonly in kidney and/or pancreas transplant patients (26%), although they were also observed, to a lesser extent, in heart (7%) and liver (4%) transplant patients. The majority of episodes of polyomavirus DNAemia were subclinical, although, in some cases, BKV DNAemia was associated with kidney rejection, and JCV DNAemia was accompanied by nonspecific symptoms. Hence, BKV and JCV DNAemia are not uncommon during the first year after kidney, heart, liver, and pancreas transplantation, and they could be associated with certain clinical syndromes in transplant patients.
AB - In this study of 263 heart, kidney, liver, and pancreas transplant patients, BK virus (BKV) and JC virus (JCV) DNAemia were observed most commonly in kidney and/or pancreas transplant patients (26%), although they were also observed, to a lesser extent, in heart (7%) and liver (4%) transplant patients. The majority of episodes of polyomavirus DNAemia were subclinical, although, in some cases, BKV DNAemia was associated with kidney rejection, and JCV DNAemia was accompanied by nonspecific symptoms. Hence, BKV and JCV DNAemia are not uncommon during the first year after kidney, heart, liver, and pancreas transplantation, and they could be associated with certain clinical syndromes in transplant patients.
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U2 - 10.1086/466532
DO - 10.1086/466532
M3 - Article
C2 - 16170751
SN - 0022-1899
VL - 192
SP - 1349
EP - 1354
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 8
ER -