Dynamic nuclear positioning requires the formation of robust connections between the cytoskeleton and components of the LINC complex, a protein assembly that spans the nuclear envelope. A new study by Lim et al. (2021) reveals the mechanism of association between the LINC complex proteins Nesprin-1/2 Giant and the cytoplasmic formin FHOD1.
Bibliographical noteFunding Information:
We wish to acknowledge the contributions of the many investigators working in this field whose work we could not cite due to space limitations. This work is supported by National Institutes of Health grant R01 GM122787 .
© 2021 Elsevier Ltd
PubMed: MeSH publication types
- Journal Article
- Research Support, N.I.H., Extramural