A Lexicon for Homeodomain-DNA Recognition

Markus Affolter; Matthew Slattery; Richard S. Mann

doi:10.1016/j.cell.2008.06.008

A Lexicon for Homeodomain-DNA Recognition

Markus Affolter
, Matthew Slattery
, Richard S. Mann

Biomedical Sciences

Research output: Contribution to journal › Short survey › peer-review

32 Scopus citations

Abstract

Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.

Original language	English (US)
Pages (from-to)	1133-1135
Number of pages	3
Journal	Cell
Volume	133
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2008.06.008
State	Published - Jun 27 2008

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10.1016/j.cell.2008.06.008

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title = "A Lexicon for Homeodomain-DNA Recognition",

abstract = "Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.",

author = "Markus Affolter and Matthew Slattery and Mann, \{Richard S.\}",

year = "2008",

month = jun,

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doi = "10.1016/j.cell.2008.06.008",

language = "English (US)",

volume = "133",

pages = "1133--1135",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier B.V.",

number = "7",

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TY - JOUR

T1 - A Lexicon for Homeodomain-DNA Recognition

AU - Affolter, Markus

AU - Slattery, Matthew

AU - Mann, Richard S.

PY - 2008/6/27

Y1 - 2008/6/27

N2 - Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.

AB - Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.

UR - https://www.scopus.com/pages/publications/45449098510

UR - https://www.scopus.com/pages/publications/45449098510#tab=citedBy

U2 - 10.1016/j.cell.2008.06.008

DO - 10.1016/j.cell.2008.06.008

M3 - Short survey

C2 - 18585344

AN - SCOPUS:45449098510

SN - 0092-8674

VL - 133

SP - 1133

EP - 1135

JO - Cell

JF - Cell

IS - 7

ER -

A Lexicon for Homeodomain-DNA Recognition

Abstract

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