A Lexicon for Homeodomain-DNA Recognition

Markus Affolter, Matthew Slattery, Richard S. Mann

Research output: Contribution to journalShort survey

22 Scopus citations

Abstract

Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.

Original languageEnglish (US)
Pages (from-to)1133-1135
Number of pages3
JournalCell
Volume133
Issue number7
DOIs
StatePublished - Jun 27 2008

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