A Lexicon for Homeodomain-DNA Recognition

Markus Affolter; Matthew Slattery; Richard S. Mann

doi:10.1016/j.cell.2008.06.008

A Lexicon for Homeodomain-DNA Recognition

Markus Affolter, Matthew Slattery, Richard S. Mann

Biomedical Sciences

Research output: Contribution to journal › Short survey › peer-review

31 Scopus citations

Abstract

Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.

Original language	English (US)
Pages (from-to)	1133-1135
Number of pages	3
Journal	Cell
Volume	133
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2008.06.008
State	Published - Jun 27 2008

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10.1016/j.cell.2008.06.008

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title = "A Lexicon for Homeodomain-DNA Recognition",

abstract = "Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.",

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AU - Affolter, Markus

AU - Slattery, Matthew

AU - Mann, Richard S.

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N2 - Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.

AB - Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors. The data underscore the complexity of determining target specificities in vivo.

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DO - 10.1016/j.cell.2008.06.008

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A Lexicon for Homeodomain-DNA Recognition

Abstract

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