Abstract
Ellipsometry and a mass transport model were used to investigate the kinetics of lipid bilayer formation on silicon dioxide surfaces from 100 nm diameter 1,2-dimyristoyl-snglycero-3-phosphocholine (DMPC) vesicles. For the range of concentrations studied, 0.025 to 0.380 mg/mL, the rate of the process was found to be concentration dependent and adsorption limited. Further experiments, particularly at concentrations > 0.380 mg/mL, presented evidence of net mass desorption as an intermediate step to supported lipid bilayer formation.
Original language | English (US) |
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Pages (from-to) | 2931-2937 |
Number of pages | 7 |
Journal | AIChE Journal |
Volume | 52 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2006 |
Externally published | Yes |
Keywords
- Bilayers
- Desorption
- Ellipsometry
- Kinetic study
- Vesicle fusion