A highly efficient synthesis of cyclaradine and its behaviour towards adenosine deaminase.

N. Katagiri; H. Kokufuda; M. Makino; Y. Matsuhashi; C. Kaneko; Robert Vince

A highly efficient synthesis of cyclaradine and its behaviour towards adenosine deaminase.

N. Katagiri, H. Kokufuda, M. Makino, Y. Matsuhashi, C. Kaneko, Robert Vince

Research output: Contribution to journal › Article › peer-review

Abstract

(+)-, (-)-, and (+/-)-Cyclaradines were efficiently synthesized from 2-aza-bicyclo[2.2.1]hept-5-en-3-one (ABH). (+)- and (+/-)-Cyclaradines were deaminated by adenosine deaminase whereas (-)-cyclaradine was not hydrolyzed under the same conditions.

Original language	English (US)
Pages (from-to)	3-4
Number of pages	2
Journal	Nucleic acids symposium series
Issue number	37
State	Published - 1997
Externally published	Yes

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title = "A highly efficient synthesis of cyclaradine and its behaviour towards adenosine deaminase.",

abstract = "(+)-, (-)-, and (+/-)-Cyclaradines were efficiently synthesized from 2-aza-bicyclo[2.2.1]hept-5-en-3-one (ABH). (+)- and (+/-)-Cyclaradines were deaminated by adenosine deaminase whereas (-)-cyclaradine was not hydrolyzed under the same conditions.",

author = "N. Katagiri and H. Kokufuda and M. Makino and Y. Matsuhashi and C. Kaneko and Robert Vince",

year = "1997",

language = "English (US)",

pages = "3--4",

journal = "Nucleic acids symposium series",

issn = "0261-3166",

publisher = "Information Retrieval",

number = "37",

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TY - JOUR

T1 - A highly efficient synthesis of cyclaradine and its behaviour towards adenosine deaminase.

AU - Katagiri, N.

AU - Kokufuda, H.

AU - Makino, M.

AU - Matsuhashi, Y.

AU - Kaneko, C.

AU - Vince, Robert

PY - 1997

Y1 - 1997

N2 - (+)-, (-)-, and (+/-)-Cyclaradines were efficiently synthesized from 2-aza-bicyclo[2.2.1]hept-5-en-3-one (ABH). (+)- and (+/-)-Cyclaradines were deaminated by adenosine deaminase whereas (-)-cyclaradine was not hydrolyzed under the same conditions.

AB - (+)-, (-)-, and (+/-)-Cyclaradines were efficiently synthesized from 2-aza-bicyclo[2.2.1]hept-5-en-3-one (ABH). (+)- and (+/-)-Cyclaradines were deaminated by adenosine deaminase whereas (-)-cyclaradine was not hydrolyzed under the same conditions.

UR - http://www.scopus.com/inward/record.url?scp=0031325943&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031325943&partnerID=8YFLogxK

M3 - Article

C2 - 9585970

AN - SCOPUS:0031325943

SN - 0261-3166

SP - 3

EP - 4

JO - Nucleic acids symposium series

JF - Nucleic acids symposium series

IS - 37

ER -

A highly efficient synthesis of cyclaradine and its behaviour towards adenosine deaminase.

Abstract

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