A high-throughput screen for porphyrin metal chelatases: Application to the directed evolution of ferrochelatases for metalloporphyrin biosynthesis

Keyphrases

• High-throughput Screening 100%
• Directed Evolution 100%
• Porphyrin 100%
• Ferrochelatase 100%
• Metalloporphyrin 100%
• Chemical Synthesis 28%
• Protoporphyrin 28%
• Escherichia Coli 14%
• Overexpression 14%
• Cancer Treatment 14%
• Biocatalysis 14%
• Biosensor Technology 14%
• Screening Approach 14%
• Heme 14%
• Overproduction 14%
• Catalytic Activity 14%
• Fluorescence-activated Cell Sorting 14%
• Metal Transport 14%
• High Production 14%
• Protein Variants 14%
• Electronic Technology 14%
• Metal Insert 14%
• In Vitro Evolution 14%
• B.subtilis 14%
• Substitution Pattern 14%
• Metal Transporters 14%
• Engineered E. Coli 14%
• Enhanced Catalytic Activity 14%
• Evolution Study 14%
• High-throughput Screening System 14%
• Recombinant E. Coli Cell 14%

Chemistry

• Porphyrin 100%
• Metalloporphyrin 100%
• High Throughput Screening 50%
• Protoporphyrin 50%
• Catalyst Activity 50%
• electronics 25%
• Heme 25%

Material Science

• Catalyst Activity 100%
• Chemical Synthesis 100%
• Biosensor 50%