A Hafnium-Based Metal-Organic Framework as a Nature-Inspired Tandem Reaction Catalyst

M. Hassan Beyzavi, Nicolaas A. Vermeulen, Ashlee J. Howarth, Samat Tussupbayev, Aaron B. League, Neil M. Schweitzer, James R. Gallagher, Ana E. Platero-Prats, Nema Hafezi, Amy A. Sarjeant, Jeffrey T. Miller, Karena W. Chapman, J. Fraser Stoddart, Christopher J. Cramer, Joseph T. Hupp, Omar K. Farha

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Abstract

Tandem catalytic systems, often inspired by biological systems, offer many advantages in the formation of highly functionalized small molecules. Herein, a new metal-organic framework (MOF) with porphyrinic struts and Hf 6 nodes is reported. This MOF demonstrates catalytic efficacy in the tandem oxidation and functionalization of styrene utilizing molecular oxygen as a terminal oxidant. The product, a protected 1,2-aminoalcohol, is formed selectively and with high efficiency using this recyclable heterogeneous catalyst. Significantly, the unusual regioselective transformation occurs only when an Fe-decorated Hf 6 node and the Fe-porphyrin strut work in concert. This report is an example of concurrent orthogonal tandem catalysis.

Original languageEnglish (US)
Pages (from-to)13624-13631
Number of pages8
JournalJournal of the American Chemical Society
Volume137
Issue number42
DOIs
StatePublished - Oct 28 2015

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    Beyzavi, M. H., Vermeulen, N. A., Howarth, A. J., Tussupbayev, S., League, A. B., Schweitzer, N. M., Gallagher, J. R., Platero-Prats, A. E., Hafezi, N., Sarjeant, A. A., Miller, J. T., Chapman, K. W., Stoddart, J. F., Cramer, C. J., Hupp, J. T., & Farha, O. K. (2015). A Hafnium-Based Metal-Organic Framework as a Nature-Inspired Tandem Reaction Catalyst. Journal of the American Chemical Society, 137(42), 13624-13631. https://doi.org/10.1021/jacs.5b08440