A guideline for effectively synthesizing and characterizing magnetic nanoparticles for advancing nanobiotechnology: A review

Mohammad Reza Zamani Kouhpanji, Bethanie J.H. Stadler

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

The remarkable multimodal functionalities of magnetic nanoparticles, conferred by their size and morphology, are very important in resolving challenges slowing the progression of nanobiotechnology. The rapid and revolutionary expansion of magnetic nanoparticles in nanobiotechnology, especially in nanomedicine and therapeutics, demands an overview of the current state of the art for synthesizing and characterizing magnetic nanoparticles. In this review, we explain the synthesis routes for tailoring the size, morphology, composition, and magnetic properties of the magnetic nanoparticles. The pros and cons of the most popularly used characterization techniques for determining the aforementioned parameters, with particular focus on nanomedicine and biosensing applications, are discussed. Moreover, we provide numerous biomedical applications and highlight their challenges and requirements that must be met using the magnetic nanoparticles to achieve the most effective outcomes. Finally, we conclude this review by providing an insight towards resolving the persisting challenges and the future directions. This review should be an excellent source of information for beginners in this field who are looking for a groundbreaking start but they have been overwhelmed by the volume of literature.

Original languageEnglish (US)
Article number2554
JournalSensors (Switzerland)
Volume20
Issue number9
DOIs
StatePublished - Apr 30 2020

Bibliographical note

Funding Information:
Funding: This research was funded by National Science Foundation (NSF), grant number CMMI-1762884.

Publisher Copyright:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

Keywords

  • Biosensing
  • Magnetic nanoparticles
  • Nanobiotechnology
  • Nanomedicine
  • Therapeutics

PubMed: MeSH publication types

  • Journal Article
  • Review

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