A functional MRI study of high-level cognition: II. The game of GO

Xiangchuan Chen, Daren Zhang, Xiaochu Zhang, Zhihao Li, Xiaomei Meng, Sheng He, Xiaoping Hu

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


GO is a board game thought to be different from chess in many aspects, most significantly in that GO emphasizes global strategy more than local battle, a property very difficult for computer programs to emulate. To investigate the neural basis of GO, functional magnetic resonance imaging (fMRI) was used to measure brain activities of subjects engaged in playing GO. Enhanced activations were observed in many cortical areas, such as dorsal prefrontal, parietal, occipital, posterior temporal, and primary somatosensory and motor areas. Quantitative analysis indicated a modest degree of stronger activation in right parietal area than in left. This type of right hemisphere lateralization differs from the modest left hemisphere lateralization observed during chess playing.

Original languageEnglish (US)
Pages (from-to)32-37
Number of pages6
JournalCognitive Brain Research
Issue number1
StatePublished - Mar 2003

Bibliographical note

Funding Information:
This research is supported by the National Nature Science Foundation of China (39928005, 39970253), National Basic Research Program of China (G1998030509), USTC Young Scholar Research Fund, NIMH R01 (MH55346), and a Sloan Research Fellowship. We thank Dr William Bart for comments on an earlier draft of the paper.


  • Functional MRI
  • GO
  • High-level cognition
  • Neural basis


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