A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity

Keyphrases

• Tumor 100%
• Tumor Penetration 100%
• Homing Peptide 100%
• Free Cysteine 100%
• Plasma Half-life 66%
• Tumor Tissue 66%
• Macromolecules 33%
• Pharmacokinetics 33%
• Amino Acids 33%
• Cyclic Peptide 33%
• Active Transport 33%
• Therapeutic Agents 33%
• Therapeutic Efficacy 33%
• Plasma Albumin 33%
• Extravascular 33%
• Vascular Wall 33%
• Bolus Injection 33%
• Cysteine Residues 33%
• Disulfide Bond 33%
• Covalent Binding 33%
• Drug Accumulation 33%
• Short Half-life 33%
• Life-limiting 33%
• Simple Strategy 33%
• Short Peptides 33%
• Tumor-targeting Peptide 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Cysteine 100%
• Neoplasm 100%
• Cyclopeptide 14%
• Amino Acid 14%
• Combination Therapy 14%
• Serum Albumin 14%
• Disulfide Bond 14%
• Extravasation 14%
• Pharmacokinetics 14%