A fluorescent coumarin derivative of α-bungarotoxin. Synthesis and spectroscopic characterization

B. A. Herman; S. M. Fernandez

doi:10.1016/0006-291X(81)90923-2

A fluorescent coumarin derivative of α-bungarotoxin. Synthesis and spectroscopic characterization

B. A. Herman
, S. M. Fernandez

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The preparation and spectroscopic characteristics of a novel coumarin derivative of α-bungarotoxin are described. The suitability of this fluorescent conjugate as a probe of cell surface topography and dynamics of acetylcholine receptors is discussed. Data are presented that show this coumarin-α-bungarotoxin conjugate to be an ideal donor fluorophore for time-resolved resonance energy transfer studies employing fluorescein as an acceptor.

Original language	English (US)
Pages (from-to)	1112-1119
Number of pages	8
Journal	Biochemical and Biophysical Research Communications
Volume	103
Issue number	3
DOIs	https://doi.org/10.1016/0006-291X(81)90923-2
State	Published - Dec 15 1981

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10.1016/0006-291X(81)90923-2

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title = "A fluorescent coumarin derivative of α-bungarotoxin. Synthesis and spectroscopic characterization",

abstract = "The preparation and spectroscopic characteristics of a novel coumarin derivative of α-bungarotoxin are described. The suitability of this fluorescent conjugate as a probe of cell surface topography and dynamics of acetylcholine receptors is discussed. Data are presented that show this coumarin-α-bungarotoxin conjugate to be an ideal donor fluorophore for time-resolved resonance energy transfer studies employing fluorescein as an acceptor.",

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AU - Fernandez, S. M.

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N2 - The preparation and spectroscopic characteristics of a novel coumarin derivative of α-bungarotoxin are described. The suitability of this fluorescent conjugate as a probe of cell surface topography and dynamics of acetylcholine receptors is discussed. Data are presented that show this coumarin-α-bungarotoxin conjugate to be an ideal donor fluorophore for time-resolved resonance energy transfer studies employing fluorescein as an acceptor.

AB - The preparation and spectroscopic characteristics of a novel coumarin derivative of α-bungarotoxin are described. The suitability of this fluorescent conjugate as a probe of cell surface topography and dynamics of acetylcholine receptors is discussed. Data are presented that show this coumarin-α-bungarotoxin conjugate to be an ideal donor fluorophore for time-resolved resonance energy transfer studies employing fluorescein as an acceptor.

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UR - https://www.scopus.com/pages/publications/0019845767#tab=citedBy

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JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

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ER -

A fluorescent coumarin derivative of α-bungarotoxin. Synthesis and spectroscopic characterization

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