A fluorescent coumarin derivative of α-bungarotoxin. Synthesis and spectroscopic characterization

B. A. Herman, S. M. Fernandez

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The preparation and spectroscopic characteristics of a novel coumarin derivative of α-bungarotoxin are described. The suitability of this fluorescent conjugate as a probe of cell surface topography and dynamics of acetylcholine receptors is discussed. Data are presented that show this coumarin-α-bungarotoxin conjugate to be an ideal donor fluorophore for time-resolved resonance energy transfer studies employing fluorescein as an acceptor.

Original languageEnglish (US)
Pages (from-to)1112-1119
Number of pages8
JournalBiochemical and Biophysical Research Communications
Volume103
Issue number3
DOIs
StatePublished - Dec 15 1981

Bibliographical note

Funding Information:
This Research was supported by

Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.

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