A few of our favorite unconfirmed ideas

John J. Marini, Luciano Gattinoni, Can Ince, Sibylle Kozek-Langenecker, Ravindra L. Mehta, Claude Pichard, Martin Westphal, Paul Wischmeyer, Jean Louis Vincent

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Medical practice is rooted in our dependence on the best available evidence from incremental scientific experimentation and rigorous clinical trials. Progress toward determining the true worth of ongoing practice or suggested innovations can be glacially slow when we insist on following the stepwise scientific pathway, and a prevailing but imperfect paradigm often proves difficult to challenge. Yet most experienced clinicians and clinical scientists harbor strong thoughts about how care could or should be improved, even if the existing evidence base is thin or lacking. One of our Future of Critical Care Medicine conference sessions encouraged sharing of novel ideas, each presented with what the speaker considers a defensible rationale. Our intent was to stimulate insightful thinking and free interchange, and perhaps to point in new directions toward lines of innovative theory and improved care of the critically ill. In what follows, a brief background outlines the rationale for each novel and deliberately provocative unconfirmed idea endorsed by the presenter.

Original languageEnglish (US)
Article numberS1
JournalCritical Care
StatePublished - Dec 18 2015

Bibliographical note

Publisher Copyright:
© 2015 Marini et al.

Fingerprint Dive into the research topics of 'A few of our favorite unconfirmed ideas'. Together they form a unique fingerprint.

Cite this