A detection system based on giant magnetoresistive sensors and high-moment magnetic nanoparticles demonstrates zeptomole sensitivity: Potential for personalized medicine

Balasubramanian Srinivasan, Yuanpeng Li, Ying Jing, Yun Hao Xu, Xiaofeng Yao, Chengguo Xing, Jian Ping Wang

Research output: Contribution to journalArticle

91 Scopus citations

Abstract

Zeptomole detector: A highly sensitive giantmagnetoresistive chip and FeCo nanoparticles can be used to linearly detect 600-4500 copies of streptavidin. Under unoptimized conditions, this system also detects human IL- 6 with a sensitivity 13-times higher than that of standard ELISA techniques.

Original languageEnglish (US)
Pages (from-to)2764-2767
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number15
DOIs
StatePublished - Mar 30 2009

Keywords

  • Biosensors
  • Giant magnetoresistance
  • Nanoparticles
  • Proteins

Fingerprint Dive into the research topics of 'A detection system based on giant magnetoresistive sensors and high-moment magnetic nanoparticles demonstrates zeptomole sensitivity: Potential for personalized medicine'. Together they form a unique fingerprint.

  • Cite this