Abstract
Spoligotyping and mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRUVNTR) analysis are the international standard techniques for molecular typing of members of the Mycobacterium tuberculosis complex. To enable the exploitation of molecular typing data for epidemiological purposes, the creation of large databases is indispensable. Here we describe mycoDB.es, a database for animal tuberculosis which forms part of the Spanish national programme for eradication of bovine tuberculosis. This database has been created as an epidemiological tool at national level and contains spoligotype patterns of 17,273 isolates clustered in 401 different spoligotypes of Mycobacterium bovis, Mycobacterium caprae and M. tuberculosis. The database offers an overview of the present spoligotypes, to a lower extent also of MIRU-VNTR types, affected animal species and furthermore of the spatial distribution of these genotypes.
Original language | English (US) |
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Pages (from-to) | 877-882 |
Number of pages | 6 |
Journal | Infection, Genetics and Evolution |
Volume | 12 |
Issue number | 4 |
DOIs | |
State | Published - Jun 1 2012 |
Bibliographical note
Funding Information:The database on animal tuberculosis is financed by and in the possession of the Spanish Ministry of the Environment, Rural and Marine Affairs (MARM) . S. Rodriguez-Campos was financed by PhD studentship AP2006-01630 of the Spanish Ministry of Education. The continuous encouragement of L. Carbajo and B. Muñóz (MARM) is very much appreciated. We would like to acknowledge the excellent technical assistance of C. Ancochea and E. Celeiro (Computer and Communication Unit, VISAVET Centre), F. Lozano, N. Moya, T. Alende, A. Gutiérrez, C. Viñolo, L. Guijarro, J. Gimeno and E. Mateos (Mycobacteria Unit, VISAVET Centre) and Tragsatec S.A. (Tragsa Group, Madrid).
Publisher Copyright:
© 2011 Elsevier B.V. All rights reserved.
Keywords
- Animal tuberculosis
- Database
- Epidemiology
- Molecular typing