A comparison of algorithms for constructing exact d-optimal designs

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An empirical comparison of existing algorithms for the computer generation of exact D-optimal experimental designs is carried out. Among algorithms considered were those due to Wyrnn, Mitchell, Fedorov, and Van Schalkwyk. A procedure for rounding off approximate designs as suggested by Kiefer is also evaluated. A modification of the Fedorov algorithm is given and shown to effect substantial decreases in the computer time required for design generation.

Original languageEnglish (US)
Pages (from-to)315-324
Number of pages10
Issue number3
StatePublished - Aug 1980

Bibliographical note

Funding Information:
R. D. Cook is a Visiting Staff Member of the Los Alamos Scientific Laboratory. This work was partially performed under the auspices of the United States Department of Energy (Contract W-7405 ENG.36).


  • Computer search
  • D-optimality
  • Exchange algorithm
  • Mixture designs
  • Optimal designs


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