A communal catalogue reveals Earth's multiscale microbial diversity

Luke R. Thompson, Jon G. Sanders, Daniel McDonald, Amnon Amir, Joshua Ladau, Kenneth J. Locey, Robert J. Prill, Anupriya Tripathi, Sean M. Gibbons, Gail Ackermann, Jose A. Navas-Molina, Stefan Janssen, Evguenia Kopylova, Yoshiki Vázquez-Baeza, Antonio González, James T. Morton, Siavash Mirarab, Zhenjiang Zech Xu, Lingjing Jiang, Mohamed F. HaroonJad Kanbar, Qiyun Zhu, Se Jin Song, Tomasz Kosciolek, Nicholas A. Bokulich, Joshua Lefler, Colin J. Brislawn, Gregory Humphrey, Sarah M. Owens, Jarrad Hampton-Marcell, Donna Berg-Lyons, Valerie McKenzie, Noah Fierer, Jed A. Fuhrman, Aaron Clauset, Rick L. Stevens, Ashley Shade, Katherine S. Pollard, Kelly D. Goodwin, Janet K. Jansson, Jack A. Gilbert, Rob Knight, Jose L. Agosto Rivera, Lisa Al-Moosawi, John Alverdy, Katherine R. Amato, Jason Andras, Largus T. Angenent, Dionysios A. Antonopoulos, Jonathan B. Clayton, Earth Microbiome Project Consortium

Research output: Contribution to journalArticle

249 Citations (Scopus)

Abstract

Our growing awareness of the microbial world's importance and diversity contrasts starkly with our limited understanding of its fundamental structure. Despite recent advances in DNA sequencing, a lack of standardized protocols and common analytical frameworks impedes comparisons among studies, hindering the development of global inferences about microbial life on Earth. Here we present a meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project. Coordinated protocols and new analytical methods, particularly the use of exact sequences instead of clustered operational taxonomic units, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multiple studies and allow us to explore patterns of diversity at an unprecedented scale. The result is both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth's microbial diversity.

Original languageEnglish (US)
Pages (from-to)457-463
Number of pages7
JournalNature
Volume551
Issue number7681
DOIs
StatePublished - Nov 23 2017

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Thompson, L. R., Sanders, J. G., McDonald, D., Amir, A., Ladau, J., Locey, K. J., ... Earth Microbiome Project Consortium (2017). A communal catalogue reveals Earth's multiscale microbial diversity. Nature, 551(7681), 457-463. https://doi.org/10.1038/nature24621

A communal catalogue reveals Earth's multiscale microbial diversity. / Thompson, Luke R.; Sanders, Jon G.; McDonald, Daniel; Amir, Amnon; Ladau, Joshua; Locey, Kenneth J.; Prill, Robert J.; Tripathi, Anupriya; Gibbons, Sean M.; Ackermann, Gail; Navas-Molina, Jose A.; Janssen, Stefan; Kopylova, Evguenia; Vázquez-Baeza, Yoshiki; González, Antonio; Morton, James T.; Mirarab, Siavash; Xu, Zhenjiang Zech; Jiang, Lingjing; Haroon, Mohamed F.; Kanbar, Jad; Zhu, Qiyun; Song, Se Jin; Kosciolek, Tomasz; Bokulich, Nicholas A.; Lefler, Joshua; Brislawn, Colin J.; Humphrey, Gregory; Owens, Sarah M.; Hampton-Marcell, Jarrad; Berg-Lyons, Donna; McKenzie, Valerie; Fierer, Noah; Fuhrman, Jed A.; Clauset, Aaron; Stevens, Rick L.; Shade, Ashley; Pollard, Katherine S.; Goodwin, Kelly D.; Jansson, Janet K.; Gilbert, Jack A.; Knight, Rob; Agosto Rivera, Jose L.; Al-Moosawi, Lisa; Alverdy, John; Amato, Katherine R.; Andras, Jason; Angenent, Largus T.; Antonopoulos, Dionysios A.; Clayton, Jonathan B.; Earth Microbiome Project Consortium.

In: Nature, Vol. 551, No. 7681, 23.11.2017, p. 457-463.

Research output: Contribution to journalArticle

Thompson, LR, Sanders, JG, McDonald, D, Amir, A, Ladau, J, Locey, KJ, Prill, RJ, Tripathi, A, Gibbons, SM, Ackermann, G, Navas-Molina, JA, Janssen, S, Kopylova, E, Vázquez-Baeza, Y, González, A, Morton, JT, Mirarab, S, Xu, ZZ, Jiang, L, Haroon, MF, Kanbar, J, Zhu, Q, Song, SJ, Kosciolek, T, Bokulich, NA, Lefler, J, Brislawn, CJ, Humphrey, G, Owens, SM, Hampton-Marcell, J, Berg-Lyons, D, McKenzie, V, Fierer, N, Fuhrman, JA, Clauset, A, Stevens, RL, Shade, A, Pollard, KS, Goodwin, KD, Jansson, JK, Gilbert, JA, Knight, R, Agosto Rivera, JL, Al-Moosawi, L, Alverdy, J, Amato, KR, Andras, J, Angenent, LT, Antonopoulos, DA, Clayton, JB & Earth Microbiome Project Consortium 2017, 'A communal catalogue reveals Earth's multiscale microbial diversity', Nature, vol. 551, no. 7681, pp. 457-463. https://doi.org/10.1038/nature24621
Thompson LR, Sanders JG, McDonald D, Amir A, Ladau J, Locey KJ et al. A communal catalogue reveals Earth's multiscale microbial diversity. Nature. 2017 Nov 23;551(7681):457-463. https://doi.org/10.1038/nature24621
Thompson, Luke R. ; Sanders, Jon G. ; McDonald, Daniel ; Amir, Amnon ; Ladau, Joshua ; Locey, Kenneth J. ; Prill, Robert J. ; Tripathi, Anupriya ; Gibbons, Sean M. ; Ackermann, Gail ; Navas-Molina, Jose A. ; Janssen, Stefan ; Kopylova, Evguenia ; Vázquez-Baeza, Yoshiki ; González, Antonio ; Morton, James T. ; Mirarab, Siavash ; Xu, Zhenjiang Zech ; Jiang, Lingjing ; Haroon, Mohamed F. ; Kanbar, Jad ; Zhu, Qiyun ; Song, Se Jin ; Kosciolek, Tomasz ; Bokulich, Nicholas A. ; Lefler, Joshua ; Brislawn, Colin J. ; Humphrey, Gregory ; Owens, Sarah M. ; Hampton-Marcell, Jarrad ; Berg-Lyons, Donna ; McKenzie, Valerie ; Fierer, Noah ; Fuhrman, Jed A. ; Clauset, Aaron ; Stevens, Rick L. ; Shade, Ashley ; Pollard, Katherine S. ; Goodwin, Kelly D. ; Jansson, Janet K. ; Gilbert, Jack A. ; Knight, Rob ; Agosto Rivera, Jose L. ; Al-Moosawi, Lisa ; Alverdy, John ; Amato, Katherine R. ; Andras, Jason ; Angenent, Largus T. ; Antonopoulos, Dionysios A. ; Clayton, Jonathan B. ; Earth Microbiome Project Consortium. / A communal catalogue reveals Earth's multiscale microbial diversity. In: Nature. 2017 ; Vol. 551, No. 7681. pp. 457-463.
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