A common source epidemic of North American blastomycosis

F. E. Tosh, K. J. Hammerman, R. J. Weeks, G. A. Sarosi

Research output: Contribution to journalArticlepeer-review

63 Scopus citations


The occurrence of pulmonary blastomycosis in 4 persons in a Minnesota town (population 464), prompted an epidemiologic investigation. The search for additional cases was concentrated in the 3 families of these 4 men and another family of close friends. The investigation revealed an additional 8 probable cases among members of the 4 families; these 8 had abnormal chest X rays, but only mild or subclinical illnesses. The 4 patients with proven blastomycosis were skin tested and showed dermal hypersensitivity to blastomycin, but not to histoplasmin. Six of the 8 with probable blastomycosis reacted to blastomycin, while only 1 reacted to histoplasmin. Serologic tests for blastomycosis were positive in only 4 of the 12 patients. All 12 recovered without specific therapy. The only activity common to the 4 families was the construction of a cabin in a wooded area on a lake shore. Attempts to isolate Blastomyces dermatitidis from the environment in the vicinity of the cabin were unsuccessful.

Original languageEnglish (US)
Pages (from-to)525-529
Number of pages5
Issue number5
StatePublished - Dec 1 1974


Dive into the research topics of 'A common source epidemic of North American blastomycosis'. Together they form a unique fingerprint.

Cite this