A cautiously optimistic vision for marker-assisted breeding

Research output: Contribution to journalShort surveypeer-review

201 Scopus citations


Even though marker-assisted selection now plays a prominent role in the field of plant breeding, examples of successful, practical outcomes are rare. It is clear that DNA markers hold great promise, but realizing that promise remains elusive. Despite innovations like better marker systems and improved genetic mapping strategies, most marker associations are not sufficiently robust for successful marker-assisted selection. In large part this is due to inadequate experimental design. Molecular breeders must reassess their research programs so that DNA marker work leads to useful selection tools and valuable germplasm. As molecular breeders adopt more rigorous experimental guidelines and ambitious goals, they also need to integrate the growing body of knowledge from genomics and bioinformatics.

Original languageEnglish (US)
Pages (from-to)505-510
Number of pages6
JournalMolecular Breeding
Issue number6
StatePublished - Dec 1 1999


  • Advanced backcross analysis
  • DNA markers
  • Marker-assisted selection
  • Monte Carlo simulation
  • Quantitative trait loci
  • Soybean cyst nematode

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