A case of rem sleep behavior disorder, narcolepsy-cataplexy, parkinsonism, and rheumatoid arthritis

Filomena I.I. Cosentino, Angela Distefano, Giuseppe Plazzi, Carlos H. Schenck, Raffaele Ferri

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1 Scopus citations

Abstract

A patient is reported in whom signs and symptoms of REM sleep behavior disorder (RBD) and narcolepsy have been associated for almost two decades with a late development of parkinsonism and rheumatoid arthritis. A 78-year-old male patient in whom RBD was first diagnosed was followed-up by clinical examination, video-polysomnography, multiple sleep latency test, cerebral magnetic resonance imaging, and dopamine transporter imaging by single-photon emission computerized tomography.The patient was found to present for almost two decades, in addition to RBD, also narcolepsy. Moreover, a late development of parkinsonism and the occurrence of rheumatoid arthritis were detected and clinically and instrumentally characterized. Patients predisposed to RBD and later parkinsonism might be susceptible to a variety of triggers that, in our patient, might have been represented by a possible latent autoimmune process leading to the development of narcolepsy with cataplexy and rheumatoid arthritis, later.

Original languageEnglish (US)
Article number572931
JournalBehavioural Neurology
Volume2014
DOIs
StatePublished - 2014

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