A case of pseudocholinesterase deficiency resulting from malnutrition

Christopher J. LaRocca, Gregory J Beilman, Martin Birch

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Pseudocholinesterase deficiencies occur because of both genetic and acquired factors. We present the case of a patient with a history of bariatric surgery and severe malnutrition who subsequently developed prolonged neuromuscular blockade after succinylcholine administration. She had markedly decreased pseudocholinesterase levels at the time of the incident, but her motor function returned to normal with supportive care. After aggressive nutritional support over multiple weeks, her pseudocholinesterase levels drastically improved. For those patients in a poor nutritional state who experience an unexpected episode of apnea or prolonged neuromuscular blockade, practitioners must always consider malnutrition-induced pseudocholinesterase deficiency as a possible etiology.

Original languageEnglish (US)
Title of host publication100 Selected Case Reports from Anesthesia and Analgesia
PublisherWolters Kluwer Health
ISBN (Electronic)9781975115333
ISBN (Print)9781975115326
DOIs
StatePublished - Jan 1 2018

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Pseudocholinesterase
Neuromuscular Blockade
Malnutrition
Succinylcholine
Bariatric Surgery
Nutritional Support
Apnea
Butyrylcholinesterase deficiency

PubMed: MeSH publication types

  • Case Reports
  • Journal Article

Cite this

LaRocca, C. J., Beilman, G. J., & Birch, M. (2018). A case of pseudocholinesterase deficiency resulting from malnutrition. In 100 Selected Case Reports from Anesthesia and Analgesia Wolters Kluwer Health. https://doi.org/10.1213/XAA.0000000000000362

A case of pseudocholinesterase deficiency resulting from malnutrition. / LaRocca, Christopher J.; Beilman, Gregory J; Birch, Martin.

100 Selected Case Reports from Anesthesia and Analgesia. Wolters Kluwer Health, 2018.

Research output: Chapter in Book/Report/Conference proceedingChapter

LaRocca, CJ, Beilman, GJ & Birch, M 2018, A case of pseudocholinesterase deficiency resulting from malnutrition. in 100 Selected Case Reports from Anesthesia and Analgesia. Wolters Kluwer Health. https://doi.org/10.1213/XAA.0000000000000362
LaRocca CJ, Beilman GJ, Birch M. A case of pseudocholinesterase deficiency resulting from malnutrition. In 100 Selected Case Reports from Anesthesia and Analgesia. Wolters Kluwer Health. 2018 https://doi.org/10.1213/XAA.0000000000000362
LaRocca, Christopher J. ; Beilman, Gregory J ; Birch, Martin. / A case of pseudocholinesterase deficiency resulting from malnutrition. 100 Selected Case Reports from Anesthesia and Analgesia. Wolters Kluwer Health, 2018.
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