A case of primary adrenal diffuse large B-cell lymphoma achieving complete remission with rituximab-CHOP chemotherapy

Kyung Min Kim, Dok Hyun Yoon, Seung Geun Lee, Sung Nam Lim, Lyu Jin Sug, Jooryung Huh, Cheolwon Suh

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Primary adrenal lymphoma is a very rare extranodal lymphoma; its clinical features consist of a high incidence of bilateral adrenal involvement and diffuse large B-cell lymphoma. We report a patient with primary bilateral adrenal diffuse large B-cell lyphoma who achieved complete remission with R-CHOP (rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy. A 52-yr-old man presented with fever and progressive fatigue for 3 months. Computed tomography (CT) scans of the abdomen and pelvis demonstrated large bilateral adrenal masses, and a needle biopsy of the left adrenal mass revealed diffuse large B-cell lymphoma. After 6 cycles of R-CHOP chemotherapy, CT scans showed no residual disease. To our knowledge, this is the second report to date of a patient with primary bilateral adrenal diffuse large B-cell lymphoma who achieved complete remission using R-CHOP chemotherapy.

Original languageEnglish (US)
Pages (from-to)525-528
Number of pages4
JournalJournal of Korean Medical Science
Volume24
Issue number3
DOIs
StatePublished - Jun 2009
Externally publishedYes

Keywords

  • Complete remission
  • Diffuse
  • Large b-Cell
  • Lymphoma
  • Primary adrenal lymphoma
  • R-CHOP

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