A 70-year-old patient with seronegative lupus nephritis: Rare case

Tuncay Dağel; Ece Meram; Emine Meltem Önal; Damla Erbıl; Mustafa Cem Bülbül; Sanem Pınar Uysal

doi:10.5222/MMJ.2018.34467

A 70-year-old patient with seronegative lupus nephritis: Rare case

Tuncay Dağel, Ece Meram, Emine Meltem Önal, Damla Erbıl, Mustafa Cem Bülbül, Sanem Pınar Uysal

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Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease known to be associated with various kinds of autoantibodies such as Antinuclear antibodies (ANA). ANA is found to be positive in most of the SLE patients. In fact, ANA positivity in serum is one of the diagnostic criteria of SLE. However, a minority of SLE patients may present with ANA negativity. We report a 70-year-old female who presented with massive edema and 10-gram/day proteinuria. Her serum antibodies for SLE were all negative and the renal biopsy showed a class V lupus nephritis. This case was unusual type of SLE due to multiple reasons namely the patient was an elderly woman, with isolated lupus nephritis and negative serology including ANA negativity.

Original language	English (US)
Pages (from-to)	54-56
Number of pages	3
Journal	Medeniyet medical journal
Volume	33
Issue number	1
DOIs	https://doi.org/10.5222/MMJ.2018.34467
State	Published - 2018
Externally published	Yes

Bibliographical note

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© 2018, Logos Medical Publishing. All rights reserved.

Keywords

Antinuclear antibody
Lupus nephritis
Systemic lupus erythematosus

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10.5222/MMJ.2018.34467

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abstract = "Systemic lupus erythematosus (SLE) is an autoimmune disease known to be associated with various kinds of autoantibodies such as Antinuclear antibodies (ANA). ANA is found to be positive in most of the SLE patients. In fact, ANA positivity in serum is one of the diagnostic criteria of SLE. However, a minority of SLE patients may present with ANA negativity. We report a 70-year-old female who presented with massive edema and 10-gram/day proteinuria. Her serum antibodies for SLE were all negative and the renal biopsy showed a class V lupus nephritis. This case was unusual type of SLE due to multiple reasons namely the patient was an elderly woman, with isolated lupus nephritis and negative serology including ANA negativity.",

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AU - Dağel, Tuncay

AU - Meram, Ece

AU - Önal, Emine Meltem

AU - Erbıl, Damla

AU - Bülbül, Mustafa Cem

AU - Uysal, Sanem Pınar

PY - 2018

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N2 - Systemic lupus erythematosus (SLE) is an autoimmune disease known to be associated with various kinds of autoantibodies such as Antinuclear antibodies (ANA). ANA is found to be positive in most of the SLE patients. In fact, ANA positivity in serum is one of the diagnostic criteria of SLE. However, a minority of SLE patients may present with ANA negativity. We report a 70-year-old female who presented with massive edema and 10-gram/day proteinuria. Her serum antibodies for SLE were all negative and the renal biopsy showed a class V lupus nephritis. This case was unusual type of SLE due to multiple reasons namely the patient was an elderly woman, with isolated lupus nephritis and negative serology including ANA negativity.

AB - Systemic lupus erythematosus (SLE) is an autoimmune disease known to be associated with various kinds of autoantibodies such as Antinuclear antibodies (ANA). ANA is found to be positive in most of the SLE patients. In fact, ANA positivity in serum is one of the diagnostic criteria of SLE. However, a minority of SLE patients may present with ANA negativity. We report a 70-year-old female who presented with massive edema and 10-gram/day proteinuria. Her serum antibodies for SLE were all negative and the renal biopsy showed a class V lupus nephritis. This case was unusual type of SLE due to multiple reasons namely the patient was an elderly woman, with isolated lupus nephritis and negative serology including ANA negativity.

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A 70-year-old patient with seronegative lupus nephritis: Rare case

Abstract

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