A 5-300MHz CMOS transceiver for multi-nuclear NMR spectroscopy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Citations (Scopus)

Abstract

This paper presents a 5-300MHz multi-nuclei NMR transceiver designed with spectroscopy for drug discovery in mind. The overall transceiver (transmitter and receiver), is implemented in 130nm CMOS, occupies an active area of 2mm 2 and consumes 12mA from a 1.5V supply. The measured phase noise for the on-chip frequency synthesizer is -110dBc at 10KHz offset when the LO frequency is 212.966MHz (∼1 H Larmor frequency at 5T). The measured input referred noise floor for the overall receiver is 3.5nV/√Hz. The receiver NMR functionality was validated using a variety of chemical samples, including adenosine triphosphaste(ATP), benzene(C6H 6) and ethanol(CH3CH2OH) in a 5T magnet. Full transceiver NMR functionality, including that of of the internal power amplifier, was validated with the help of a 0.3mL H2O sample.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE 2012 Custom Integrated Circuits Conference, CICC 2012
DOIs
StatePublished - Nov 26 2012
Event34th Annual Custom Integrated Circuits Conference, CICC 2012 - San Jose, CA, United States
Duration: Sep 9 2012Sep 12 2012

Publication series

NameProceedings of the Custom Integrated Circuits Conference
ISSN (Print)0886-5930

Other

Other34th Annual Custom Integrated Circuits Conference, CICC 2012
CountryUnited States
CitySan Jose, CA
Period9/9/129/12/12

Fingerprint

Nuclear magnetic resonance spectroscopy
Transmitters
Nuclear magnetic resonance
Frequency synthesizers
Phase noise
Power amplifiers
Magnets
Benzene
Ethanol
Spectroscopy
Drug Discovery

Cite this

Kim, J., Hammer, B., & Harjani, R. (2012). A 5-300MHz CMOS transceiver for multi-nuclear NMR spectroscopy. In Proceedings of the IEEE 2012 Custom Integrated Circuits Conference, CICC 2012 [6330645] (Proceedings of the Custom Integrated Circuits Conference). https://doi.org/10.1109/CICC.2012.6330645

A 5-300MHz CMOS transceiver for multi-nuclear NMR spectroscopy. / Kim, Jaehyup; Hammer, Bruce; Harjani, Ramesh.

Proceedings of the IEEE 2012 Custom Integrated Circuits Conference, CICC 2012. 2012. 6330645 (Proceedings of the Custom Integrated Circuits Conference).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kim, J, Hammer, B & Harjani, R 2012, A 5-300MHz CMOS transceiver for multi-nuclear NMR spectroscopy. in Proceedings of the IEEE 2012 Custom Integrated Circuits Conference, CICC 2012., 6330645, Proceedings of the Custom Integrated Circuits Conference, 34th Annual Custom Integrated Circuits Conference, CICC 2012, San Jose, CA, United States, 9/9/12. https://doi.org/10.1109/CICC.2012.6330645
Kim J, Hammer B, Harjani R. A 5-300MHz CMOS transceiver for multi-nuclear NMR spectroscopy. In Proceedings of the IEEE 2012 Custom Integrated Circuits Conference, CICC 2012. 2012. 6330645. (Proceedings of the Custom Integrated Circuits Conference). https://doi.org/10.1109/CICC.2012.6330645
Kim, Jaehyup ; Hammer, Bruce ; Harjani, Ramesh. / A 5-300MHz CMOS transceiver for multi-nuclear NMR spectroscopy. Proceedings of the IEEE 2012 Custom Integrated Circuits Conference, CICC 2012. 2012. (Proceedings of the Custom Integrated Circuits Conference).
@inproceedings{49e37f24ae8046c8b52d54740b3453dd,
title = "A 5-300MHz CMOS transceiver for multi-nuclear NMR spectroscopy",
abstract = "This paper presents a 5-300MHz multi-nuclei NMR transceiver designed with spectroscopy for drug discovery in mind. The overall transceiver (transmitter and receiver), is implemented in 130nm CMOS, occupies an active area of 2mm 2 and consumes 12mA from a 1.5V supply. The measured phase noise for the on-chip frequency synthesizer is -110dBc at 10KHz offset when the LO frequency is 212.966MHz (∼1 H Larmor frequency at 5T). The measured input referred noise floor for the overall receiver is 3.5nV/√Hz. The receiver NMR functionality was validated using a variety of chemical samples, including adenosine triphosphaste(ATP), benzene(C6H 6) and ethanol(CH3CH2OH) in a 5T magnet. Full transceiver NMR functionality, including that of of the internal power amplifier, was validated with the help of a 0.3mL H2O sample.",
author = "Jaehyup Kim and Bruce Hammer and Ramesh Harjani",
year = "2012",
month = "11",
day = "26",
doi = "10.1109/CICC.2012.6330645",
language = "English (US)",
isbn = "9781467315555",
series = "Proceedings of the Custom Integrated Circuits Conference",
booktitle = "Proceedings of the IEEE 2012 Custom Integrated Circuits Conference, CICC 2012",

}

TY - GEN

T1 - A 5-300MHz CMOS transceiver for multi-nuclear NMR spectroscopy

AU - Kim, Jaehyup

AU - Hammer, Bruce

AU - Harjani, Ramesh

PY - 2012/11/26

Y1 - 2012/11/26

N2 - This paper presents a 5-300MHz multi-nuclei NMR transceiver designed with spectroscopy for drug discovery in mind. The overall transceiver (transmitter and receiver), is implemented in 130nm CMOS, occupies an active area of 2mm 2 and consumes 12mA from a 1.5V supply. The measured phase noise for the on-chip frequency synthesizer is -110dBc at 10KHz offset when the LO frequency is 212.966MHz (∼1 H Larmor frequency at 5T). The measured input referred noise floor for the overall receiver is 3.5nV/√Hz. The receiver NMR functionality was validated using a variety of chemical samples, including adenosine triphosphaste(ATP), benzene(C6H 6) and ethanol(CH3CH2OH) in a 5T magnet. Full transceiver NMR functionality, including that of of the internal power amplifier, was validated with the help of a 0.3mL H2O sample.

AB - This paper presents a 5-300MHz multi-nuclei NMR transceiver designed with spectroscopy for drug discovery in mind. The overall transceiver (transmitter and receiver), is implemented in 130nm CMOS, occupies an active area of 2mm 2 and consumes 12mA from a 1.5V supply. The measured phase noise for the on-chip frequency synthesizer is -110dBc at 10KHz offset when the LO frequency is 212.966MHz (∼1 H Larmor frequency at 5T). The measured input referred noise floor for the overall receiver is 3.5nV/√Hz. The receiver NMR functionality was validated using a variety of chemical samples, including adenosine triphosphaste(ATP), benzene(C6H 6) and ethanol(CH3CH2OH) in a 5T magnet. Full transceiver NMR functionality, including that of of the internal power amplifier, was validated with the help of a 0.3mL H2O sample.

UR - http://www.scopus.com/inward/record.url?scp=84869412401&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84869412401&partnerID=8YFLogxK

U2 - 10.1109/CICC.2012.6330645

DO - 10.1109/CICC.2012.6330645

M3 - Conference contribution

AN - SCOPUS:84869412401

SN - 9781467315555

T3 - Proceedings of the Custom Integrated Circuits Conference

BT - Proceedings of the IEEE 2012 Custom Integrated Circuits Conference, CICC 2012

ER -